Destined to make a leap (5)
I believe the answer is:
bound
This clue is a double definition.
'destined' is the first definition.
(I've seen this before)
'a leap' is the second definition.
('bound' can be a synonym of 'leap')
'to make' is the link.
(Other definitions for bound that I've seen before include "Place restrictions" , "Tied - leap" , "Tied -- limit" , "Bob < sure < to be heading for" , "demarcation" .)