Direct course of male ox (5)
I believe the answer is:
steer
I believe this is a double definition.
'direct course of' is the first definition.
(to steer is to direct)
'male ox' is the second definition.
(steer can mean a male ox)
(Other definitions for steer that I've seen before include "farm animal" , "Guide the bull" , "Direct; bullock" , "Navigate" , "beef producer" .)