Doctor got up in a bad mood (6)
I believe the answer is:
morose
'in a bad mood' is the definition.
(morose means sad or in a bad mood)
'doctor got up' is the wordplay.
'doctor' becomes 'mo' (medical officer).
'got up' becomes 'rose' (past tense of 'raise').
'mo'+'rose'='MOROSE'
(Other definitions for morose that I've seen before include "blue" , "grouchy" , "Sullen and ill-tempered" , "Melancholy" , "Gloomy and unsociable" .)