Donne works in great quantities (2,3)
I believe the answer is:
no end
'donne works in great quantities' is the definition.
I can't judge whether this definition defines the answer.
'donne works' is the wordplay.
'works' indicates an anagram (letters worked into a new form).
'donne' anagrammed gives 'NO END'.
Can you help me to learn more?
(Other definitions for no end that I've seen before include "Very much (unfinished?)" , "Without limit" , "Non-stop" , "Enormously" , "detailed?" .)