Entertainment district of London (4)
I believe the answer is:
soho
'entertainment district of london' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for soho that I've seen before include "Entertainment district in London's West End" , "London's former Bohemia" , "Part of London and NY" , "London night life area" , "Huntsman's call - area of London" .)