Eponym for an annual prize for American humor (5)

I believe the answer is:

twain

(Other definitions for twain that I've seen before include "Kipling never expected to meet" , "Mark . . . . . was the pen name of Samuel Langhorne Clemens" , "Mark -, Huckleberry Finn author" , "Pen name of Samuel Langhorne Clemens, d. 1910)" , "II?" .)

I've seen this clue in The New York Times.

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