Expend (3)
'expend' is the definition.
(I know that expend can be written as use)
This is all the clue.
(Other definitions for use that I've seen before include "Operate" , "Consume; deploy" , "Expend in amusement" , "Avail oneself of" , "Profit" .)
'expend' is the definition.
(I know that use up is a kind of expend)
This is the entire clue.
(Other definitions for use up that I've seen before include "Completely consume" , "Exhaust (resources)" , "Entirely consume" , "Expend" , "Finish, exhaust" .)