Farthest spot among others (8)
I believe the answer is:
remotest
'farthest' is the definition.
(thesaurus)
'spot among others' is the wordplay.
'spot' becomes 'mote' (I've seen this before).
'among' is an insertion indicator.
'others' becomes 'rest' (I've seen this before).
'mote' put within 'rest' is 'REMOTEST'.
(Other definitions for remotest that I've seen before include "Furthest away, most distant" , "Terse mot (anag)" .)