Female, busy type, finally down in drinking den (7)
I believe the answer is:
shebeen
'drinking den' is the definition.
(I've seen this before)
'female busy type finally down' is the wordplay.
'female' becomes 'she' ('she' refers to a woman).
'busy type' becomes 'bee' (busy as a bee).
'finally' suggests the final letters.
The final letter of 'down' is 'n'.
'she'+'bee'+'n'='SHEBEEN'
'in' acts as a link.
(Other definitions for shebeen that I've seen before include "in which spirits may be found" , "Alcohol sold without licence" , "Unlicensed drinking establishment" , "Unlicenced house selling alcohol (Ireland)" , "scene with moonshine?" .)