First, original (6)
I believe the answer is:
primal
This clue is a double definition.
'first' is the first definition.
(primal can mean early or first)
'original' is the second definition.
(synonyms)
(Other definitions for primal that I've seen before include "From a very early time" , "First; primitive" , "Original - basic" , "Original or primitive" , "Most important (scream therapy?)" .)