Food shortage: amen if resolved (6)
I believe the answer is:
famine
'food shortage' is the definition.
(I've seen this before)
'amen if resolved' is the wordplay.
'resolved' is an anagram indicator.
'amen'+'if'='amenif'
'amenif' anagrammed gives 'FAMINE'.
(Other definitions for famine that I've seen before include "Severe and widespread shortage of food" , "Severe food scarcity" , "Extreme dearth of food" , "Severe shortage of food for many" , "Starvation" .)