Foot in fixed position before toe is manipulated (7)
I believe the answer is:
tootsie
'foot' is the definition.
(I've seen this before)
'in fixed position before toe is manipulated' is the wordplay.
'in fixed position' becomes 'to' (as in a door which is 'to').
'before' says to put letters next to each other.
'manipulated' indicates an anagram.
'toe'+'is'='toeis'
'toeis' anagrammed gives 'otsie'.
'to'+'otsie'='TOOTSIE'
(Other definitions for tootsie that I've seen before include "Part of foot" , "Film with Dustin Hoffman" , "Foot or toe (childish)" , "Funnily enough, foot" , "Child's word for toe" .)