Frustrating, with grant having been adjusted (9)
I believe the answer is:
thwarting
'frustrating' is the definition.
('thwart' can be a synonym of 'frustrate')
'with grant having been adjusted' is the wordplay.
'having been adjusted' indicates anagramming the letters.
'with'+'grant'='withgrant'
'withgrant' is an anagram of 'THWARTING'.
(Other definitions for thwarting that I've seen before include "Blocking" , "Frustrating, impeding" , "getting in the way" , "Preventing (someone doing something)" .)