Genetic variant (6)

I believe the answer is:

strain

(Other definitions for strain that I've seen before include "Tension - tune" , "'Stress, tension (6)'" , "Tension - stock" , "Remove by passing through a filter" , "Pass through a colander" .)

I've seen this clue in the Universal, the Jonesin', The Washington Post, The Wall Street Journal, the L.A. Times Daily and The New York Times.

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