Giant clone's mutation of DNA (10)

I believe the answer is:

congenital

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'giant clone's mutation of dna' is the definition.
I can't judge whether this defines the answer.

'giant clone's mutation' is the wordplay.
'mutation' indicates anagramming the letters.
'giant'+'clone'='giantclone'
'giantclone' with letters rearranged gives 'CONGENITAL'.

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(Another definition for congenital that I've seen is " Absolute".)

I've seen this clue in the Sydney Morning Herald.

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