Great misfortune for Jane? (8)

I believe the answer is:

calamity

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'great misfortune' is the definition.
(I've seen this before)

I cannot understand how the remainder of the clue works.

(Other definitions for calamity that I've seen before include "Disaster, sudden great misfortune" , "Event resulting in great loss and misfortune" , "Catastrophe" , "Disaster, extreme misfortune" , "Tragedy" .)

I've seen this clue in The Globe and Mail.

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