Guided a sanctimonious fellow round a lot (7)
I believe the answer is:
piloted
'guided' is the definition.
(piloting is a kind of guiding)
'a sanctimonious fellow round a lot' is the wordplay.
'a sanctimonious' becomes 'pi' (British abbreviation for pious).
'fellow' becomes 'ed' (I've seen this in other clues).
'round' indicates putting letters inside.
'pi'+'ed'='pied'
'pied' going around 'lot' is 'PILOTED'.
(Other definitions for piloted that I've seen before include "Tested" , "Guided" .)