Hardening bone clogs spinning slicers (9)
I believe the answer is:
sclerosis
'hardening' is the definition.
(thesaurus)
'bone clogs spinning slicers' is the wordplay.
I cannot quite see how this works, but
'bone' could be 'os' (Latin for 'bone') and 'os' is present in the answer.
an anagram of 'slicers' is 'scleris' which is located in the left over letters.
No letters remain.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for sclerosis that I've seen before include "Hardening of body tissue" , "Hardening (of arteries etc) - cross isle (anag)" .)