Help whistleblower to frame story (6)
I believe the answer is:
relief
'help' is the definition.
(I know that relief is a type of help)
'whistleblower to frame story' is the wordplay.
'whistleblower' becomes 'ref' (a referee blows a whistle).
'to frame' is an insertion indicator.
'story' becomes 'lie' (story can mean a fabrication).
'ref' placed around 'lie' is 'RELIEF'.
(Other definitions for relief that I've seen before include "Assistance given to people in need" , "Alleviation - charity - raised decoration" , "Pleasure at removal of anxiety" , "Lessening or removal of pain" , "Break" .)