Hold area with a quarter (5)
I believe the answer is:
seize
'hold' is the definition.
(thesaurus)
'area with a quarter' is the wordplay.
I cannot really understand how this works, but
'quarter' could be 'se' and 'se' is located in the answer.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for seize that I've seen before include "Capture" , "Nobble" , "Take by force" , "Grasp suddenly" , "a sweet number in Grenoble, say" .)