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In distress, she's visibly upset (6)

Ross

I believe the answer is:

sister

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'in' is the definition.
Both the definition and answer are adjectives. Perhaps there's an association between them I don't understand?

I cannot understand how the rest of the clue works.

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(Other definitions for sister that I've seen before include "Nurse, nun and sibling" , "of the same origin" , "trade union member?" , "Close female relative" , "habits' - one who has them" .)

I've seen this clue in the Evening Standard.
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