Indicate it's despicable (4)
I believe the answer is:
mean
I believe this clue is a double definition.
'indicate' is the first definition.
(I've seen this in another clue)
'despicable' is the second definition.
(I've seen this before)
'it's' is the link.
(Other definitions for mean that I've seen before include "intimate" , "Aim - low - average" , "Despicable" , "Stingy; five Dn" , "Close" .)