Inflamed, aching (4)
I believe the answer is:
sore
I believe this clue is a double definition.
'inflamed' is the first definition.
(I've seen this in another clue)
'aching' is the second definition.
(with aches)
(Other definitions for sore that I've seen before include "Painful spot" , "Painful or tender" , "Feeling pain or informally angry" , "Hurtful to the touch, like rose" , "Painfully sensitive" .)