Injure artist during pirouette (6)
I believe the answer is:
sprain
'injure' is the definition.
(I know that sprain is a kind of injure)
'artist during pirouette' is the wordplay.
'artist' becomes 'RA' (Royal Academician, member of Royal Academy of Arts).
'during' is an insertion indicator.
'pirouette' becomes 'spin' (I've seen this in another clue).
'ra' inserted within 'spin' is 'SPRAIN'.
(Other definitions for sprain that I've seen before include "Wrenching (of a muscle)" , "Injury to ligaments" , "Minor muscular injury" , "Wrench (an ankle) 6)" , "Pulled muscle" .)