Instrument I love endlessly playing at home (6)
I believe the answer is:
violin
'instrument' is the definition.
(I know that Violin is a instrument)
'i love endlessly playing at home' is the wordplay.
'endlessly' means to remove the last letter.
'playing' indicates an anagram.
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'i'+'love'='ilove'
'ilove' with its last letter removed is 'ilov'.
'ilov' is an anagram of 'viol'.
'viol'+'in'='VIOLIN'
(Other definitions for violin that I've seen before include "Instrument with four strings" , "Instrument with bow" , "A stringed musical instrument, say a Stradivarius" , "Menuhin's instrument" , "Nigel Kennedy instrument" .)