Italian city designed for romance? (7)
I believe the answer is:
cremona
'italian city' is the definition.
(Cremona is a city in Italy)
'designed for romance?' is the wordplay.
'designed for' is an anagram indicator (letters re-designed).
'romance' is an anagram of 'CREMONA'.
(Other definitions for cremona that I've seen before include "Northern Italian city" , "No cream in this Italian city" , "Italian city famed for its violins" , "...and the Italian home of both Stradivari and the Amatis" , "Guarneri's place" .)