King Edward possibly seemed upset to take over? (4)
I believe the answer is:
spud
'king edward' is the definition.
(I've seen this before)
'seemed upset to take over?' is the wordplay.
'to take' says the answer is hidden in the clue (I've seen 'taking' mean this (the answer is carried or taken by the clue)).
'over?' is a reversal indicator (I've seen 'over ' mean this).
'dups' is hidden within 'seemed upset'.
'dups' written backwards gives 'SPUD'.
'possibly' acts as a link.
(Other definitions for spud that I've seen before include "King Edward, e.g." , "Commoner's King Edward?" , "Murphy" , "The popular potato" , "short, stocky person" .)