Large university with originality, but no energy, raking in money (9)
I believe the answer is:
lucrative
'raking in money' is the definition.
(lucrative can mean generating a lot of money)
'large university with originality but no energy' is the wordplay.
'large' becomes 'L' (eg in clothes sizes).
'university' becomes 'u' (abbreviation for university).
'with originality' becomes 'creative' (creative can mean original or innovative).
'but no' is a deletion indicator.
'energy' becomes 'e' (physics symbol as in E=mc2).
'creative' with 'e' taken out is 'crative'.
'l'+'u'+'crative'='LUCRATIVE'
(Other definitions for lucrative that I've seen before include "Revictual (anag.)" , "Making a great profit" , "Making money" , "Highly profitable" , "rewarding" .)