Learned establishment may reflect limits of unilateralism (6)
I believe the answer is:
museum
'learned establishment' is the definition.
The answer and definition can be both man-made objects as well as being singular nouns.
Perhaps you can see an association between them that I can't see?
'reflect limits of unilateralism' is the wordplay.
'reflect' becomes 'muse' (synonyms).
'limits of' suggests removing the centre.
'unilateralism' with its middle taken out is 'um'.
'muse'+'um'='MUSEUM'
'may' acts as a link.
Can you help me to learn more?
(Other definitions for museum that I've seen before include "British possibly" , "Building in which historical or scientific items are exhibited" , "Use mum (anag.)" , "Place to keep and exhibit objects of interest" , "Where items of interest may be seen or studied" .)