Loaded nurse chasing after young man (5)
I believe the answer is:
laden
'loaded' is the definition.
(I know that loaded can be written as laden)
'nurse chasing after young man' is the wordplay.
'nurse' becomes 'EN' (abbreviation for enrolled nurse).
'chasing after' is a charade indicator (letters next to each other).
'young man' becomes 'lad' (lad can mean a boy or young man).
'en' after 'lad' is 'LADEN'.
(Other definitions for laden that I've seen before include "full cargo ship" , "charged a lot" , "Freighted" , "Weighed down with much cargo" , "Carrying a load" .)