Loathing calluses when cycling (5)
I believe the answer is:
scorn
'loathing' is the definition.
The answer and definition can be both feelings as well as being singular nouns.
Maybe there's an association between them I don't understand?
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for scorn that I've seen before include "Open disrespect" , "Disdain or derision" , "Slight" , "Mocking contempt" , "Open contempt, disdain" .)