Made to react, perhaps, by the Editor (7)
I believe the answer is:
created
'made' is the definition.
('create' can be a synonym of 'make')
'react perhaps by the editor' is the wordplay.
'perhaps' indicates anagramming the letters.
'by' is a charade indicator (letters next to each other).
'the editor' becomes 'ed' (abbreviation).
'react' anagrammed gives 'creat'.
'creat'+'ed'='CREATED'
'to' acts as a link.
(Other definitions for created that I've seen before include "Made a fuss" , "Originated" , "Made, generated" , "Devised" , "Brought into existence" .)