Managed most of trial venue in spite (7)
I believe the answer is:
rancour
'spite' is the definition.
(I've seen this before)
'managed most of trial venue' is the wordplay.
'managed' becomes 'ran' (both can mean organised or was in charge of).
'most of trial venue' becomes 'cour' (I can't explain this - if you can you should give a lot more credence to this answer).
'ran'+'cour'='RANCOUR'
'in' acts as a link.
Can you help me to learn more?
(Other definitions for rancour that I've seen before include "Deep-seated bitterness" , "Bitterness or resentfulness" , "Long-lasting bitterness" , "Acrimony" , "Bitter feeling or ill will" .)