Manila's wild creatures (7)
I believe the answer is:
animals
'creatures' is the definition.
(I know this)
'manila's wild' is the wordplay.
'wild' indicates an anagram.
'manilas' with letters rearranged gives 'ANIMALS'.
(Other definitions for animals that I've seen before include "brutal men" , "Beasts, creatures" , "Wild beasts" , "Living beings" , "Brutes" .)