Mental make up of Republican leaving jumbled cyphers (6)
I believe the answer is:
psyche
'mental make up' is the definition.
(someone's mind or psychology)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for psyche that I've seen before include "Human faculty for thought - Cupid's lover" , "Sole and spirit" , "Wife of Cupid" , "The soul, spirit or mind" , "A beautiful girl" .)