Nothing originally conceived by politician works (7)
I believe the answer is:
factory
'works' is the definition.
(factory is a kind of works)
'nothing originally conceived by politician' is the wordplay.
'nothing' becomes 'fa'.
'originally' suggests taking the first letters.
'by' means one lot of letters go next to another.
'politician' becomes 'tory' (I've seen this before**).
The initial letter of 'conceived' is 'c'.
'fa'+'c'+'tory'='FACTORY'
(Other definitions for factory that I've seen before include "Works" , "Manufacturing plant" , "mill" , "Place for production" , "Building used for making or assembling items" .)