Old adversary quite devoid of it (7)
I believe the answer is:
antique
'old' is the definition.
(similar in meaning)
'adversary quite devoid of it' is the wordplay.
'adversary' becomes 'anti' (I've seen this before).
'devoid of' indicates named letters should be taken away.
'quite' with 'it' taken out is 'que'.
'anti'+'que'='ANTIQUE'
(Other definitions for antique that I've seen before include "Old item of value" , "Old collectable item" , "Old and valuable item" , "Lovely old piece" , "Ancient object" .)