On poor advice, at wit’s end, perhaps (9)
I believe the answer is:
activated
'on poor' is the definition.
I can't judge whether this defines the answer.
'advice at wit's end perhaps' is the wordplay.
'end' says to take the final letters.
'perhaps' indicates anagramming the letters.
The final letter of 'wit' is 't'.
'advice'+'at'+'t'='adviceatt'
'adviceatt' with letters rearranged gives 'ACTIVATED'.
Can you help me to learn more?
(Other definitions for activated that I've seen before include "Made operative" , "Turned on" .)