Overdose in graduate college, top grade white powder (6,4)
I believe the answer is:
baking soda
'white powder' is the definition.
The definition and answer can be both substances as well as being singular nouns.
Maybe they are linked in a way I don't understand?
'overdose in graduate college top grade' is the wordplay.
'overdose' becomes 'o.d.' (synonyms).
'in' means one lot of letters goes inside another.
'graduate college' becomes 'bakings' (I am not sure about this - if you are sure you should believe this answer much more).
'top grade' becomes 'A' (top academic grade).
'bakings'+'a'='bakingsa'
'od' going into 'bakingsa' is 'BAKING-SODA'.
Can you help me to learn more?
(Other definitions for baking soda that I've seen before include "possible antacid" , "Common name for sodium bicarbonate" .)