Pass over a rugged region (6)

I believe the answer is:

ignore

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'pass over' is the definition.
(I've seen this in another clue)

'a rugged region' is the wordplay.
'region' anagrams to 'IGNORE'.
But, I am unsure how this is indicated.

Can you help me to learn more?

(Other definitions for ignore that I've seen before include "Cut head off" , "Deliberately take no notice" , "Region in which to snub" , "Deliberately disregard" , "Intentionally disregard" .)

I've seen this clue in the Evening Standard.

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