Passed over hard liquor when depressed (10)
I believe the answer is:
dispirited
'depressed' is the definition.
(I know that depressed can be written as dispirited)
'passed over hard liquor when' is the wordplay.
'passed' becomes 'did' (doing is a kind of passing).
'over' indicates putting letters inside.
'hard liquor' becomes 'spirit' (I've seen this before).
'when' becomes 'e' (I've seen this in other clues).
'spirit'+'e'='spirite'
'did' enclosing 'spirite' is 'DISPIRITED'.
(Other definitions for dispirited that I've seen before include "Dejected, discouraged" , "low" .)