Rogue is small and effeminate (5)
I believe the answer is:
scamp
'rogue' is the definition.
(I've seen this before)
'small and effeminate' is the wordplay.
'small' becomes 's' (abbreviation - e.g. clothes size).
'and' means one lot of letters go next to another.
'effeminate' becomes 'camp' (I've seen this before).
's'+'camp'='SCAMP'
'is' is the link.
(Other definitions for scamp that I've seen before include "Impish youngster" , "Mischief-maker" , "Mischievous child (colloq.)" , "Rogue - perform inadequately" , "A young rascal misbehaving in camps" .)