Rubbish drug experience with ecstasy (5)
I believe the answer is:
tripe
'rubbish' is the definition.
(both can mean nonsense)
'drug experience with ecstasy' is the wordplay.
'drug experience' becomes 'trip' (as in tripping on drugs).
'with' is a charade indicator (letters next to each other).
'ecstasy' becomes 'E' (informal term for the drug).
'trip'+'e'='TRIPE'
(Other definitions for tripe that I've seen before include "Edible nonsense?" , "Ruminant's stomach lining" , "Lining of the stomach of a cow as food" , "Rubbish; offal" , "Garbage" .)