Run – and come to grief (4)

I believe the answer is:

trip

I'm a little stuck... Click here to teach me more about this clue!

'run' is the definition.
(thesaurus)

I cannot understand how the remainder of the clue works.

(Other definitions for trip that I've seen before include "Excursion (while on drugs?)" , "Journey - cause to stumble" , "Catch one's foot" , "Run with light steps" , "Hallucinogenic drug experience - lose one's balance" .)

I've seen this clue in the Evening Standard.

Want a hint initially instead of a full solution? Install my app