Run from politician going after a Democrat (10)
I believe the answer is:
administer
'run' is the definition.
(I've seen this before)
'politician going after a democrat' is the wordplay.
'politician' becomes 'minister' (I've seen this before).
'going after' says to put letters next to each other.
'democrat' becomes 'd'.
'a'+'d'='ad'
'minister' put after 'ad' is 'ADMINISTER'.
'from' acts as a link.
(Other definitions for administer that I've seen before include "conduct" , "Dispense" , "Run" , "Handle" , "control" .)