Sadly I must hear about male medical condition (10)
I believe the answer is:
rheumatism
'medical condition' is the definition.
(rheumatism is a type of medical condition)
'sadly i must hear about male' is the wordplay.
'sadly' indicates anagramming the letters.
'about' is an insertion indicator.
'male' becomes 'm' (common abbreviation).
'i'+'must'+'hear'='imusthear'
'imusthear' is an anagram of 'rheuatism'.
'rheuatism' placed around 'm' is 'RHEUMATISM'.
(Other definitions for rheumatism that I've seen before include "Inflammation of the joints" , "Joint affliction" , "ailment" .)