Scrub Charlie clean, possibly (6)
I believe the answer is:
cancel
'scrub' is the definition.
(I've seen this in another clue)
'charlie clean possibly' is the wordplay.
'charlie' becomes 'c' (phonetic alphabet: alpha, bravo, charlie etc.).
'possibly' indicates anagramming the letters.
'clean' with letters rearranged gives 'ancel'.
'c'+'ancel'='CANCEL'
(Other definitions for cancel that I've seen before include "Discontinue" , "Go for an annulment" , "Call off (arranged event)" , "Declare null and void" , "Annul or rescind" .)