Second large worker has inclination (5)
I believe the answer is:
slant
'inclination' is the definition.
(slant is a kind of inclination)
'second large worker' is the wordplay.
'second' becomes 's' (common abbreviation).
'large' becomes 'L' (eg in clothes sizes).
'worker' becomes 'ant' (worker is a type of ant).
's'+'l'+'ant'='SLANT'
'has' is the link.
(Other definitions for slant that I've seen before include "Tilt - bias" , "Angle; incline" , "Slope - bias" , "Lean, point of view" , "Inclination" .)