Seville, it may seem, can be right in Genoa! (6)
I believe the answer is:
orange
'seville it may seem can' is the definition.
I can't judge whether this defines the answer.
'right in genoa' is the wordplay.
I cannot quite understand how this works, but
'right' could be 'r' (common abbreviation) and 'r' is found within the answer.
an anagram of 'genoa' is 'oange' which is present in the left over letters.
This accounts for all the letters.
This may be the basis of clue (or it may be nonsense).
'be' acts as a link.
Can you help me to learn more?
(Other definitions for orange that I've seen before include "Between red and yellow on the spectrum" , "Mandarin?" , "Kind of sauce" , "A rainbow colour" , "divided internally, naturally" .)