Sewing instrument; annoy (6)
I believe the answer is:
needle
I believe this clue is a double definition.
'sewing instrument' is the first definition.
(I've seen this before)
'annoy' is the second definition.
(I know this)
(Other definitions for needle that I've seen before include "Sharp pointed implement" , "point" , "Irritate; pine leaf" , "Sewing implement used to annoy" , "Implement with eye" .)